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  • CRISPR People
    CRISPR People


    Price: 17.99 £ | Shipping*: 3.99 £
  • Art and Biotechnology : Viral Culture from CRISPR to COVID
    Art and Biotechnology : Viral Culture from CRISPR to COVID

    This interdisciplinary anthology examines the relationship between developments in biotechnology and both artistic and literary innovation, focussing in particular on how newfound molecular technologies and knowledge regimes, such as CRISPR gene editing, alter conceptions of what it means to be human. The book presents 21 essays, split across four parts, from a coterie of artists, theorists, historians and scientists which examine the symbiotic relationship between humans, animals, and viruses as well as the impossibility of germ-free existence. The essays in this volume are urgent in their topicality, embodying the exhilarating yet alarming zeitgeist of contemporary nonhuman-to-human viral transmission and gene editing technologies.Ultimately, Art and Biotechnology reveals how art and biotechnology influence each other and how art has shaped the discussion around gene editing and the socio-cultural aspects of the Covid-19 pandemic.It is essential reading for students and researchers focussing on science and art, environmental humanities, and ethics.

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  • CRISPR : A Powerful Way to Change DNA
    CRISPR : A Powerful Way to Change DNA

    We can change the world with genetic modification—but should we? CRISPR stands for clustered regularly interspaced short palindromic repeats.If it sounds complicated, it is—but it’s also one of the most powerful ways we can shape the future. And it’s poised to completely upend the way we think about science. Author Yolanda Ridge tackles this topic in a friendly and accessible tone, with two introductory chapters covering the basics of DNA and genetic modification before taking readers through the ways that this ground-breaking science could affect them by potentially:- eliminating diseases like malaria and cancer, - improving the stability of our food supply, and- helping to manage conservation efforts for threatened animals and environments. But all of these possible advancements come with risks, the biggest being that the consequences are unknown.Chapters end with “Stop, Go, Yield” sections encouraging readers to consider the pros and cons of using CRISPR. “Cutting Questions” give readers the opportunity to further reflect on the ethics of the science. CRISPR is a game changer. This important book, with detailed scientific illustrations, brings much needed clarity to a topic that will affect readers for generations to come.

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  • CRISPR for Climate-Smart and Sustainable Agriculture
    CRISPR for Climate-Smart and Sustainable Agriculture

    CRISPR for Climate-Smart and Sustainable Agriculture summarizes the current genome editing technology being used in food and energy crops.It presents methods and applications of CRISPR tools for breeding climate-smart and stress-tolerant crops that are better able to resist biotic and abiotic stressors due to climate change. Gene editing tools are increasingly seen as options for improving plant health and productivity.CRISPR is one such emerging and quickly advancing crucial technology for the research field of plant physiology, plant molecular biology, and crop breeding.CRISPR for Climate-Smart and Sustainable Agriculture focuses on genetic engineering using CRISPR technology for precision breeding of crops to achieve climate resilience, stress tolerance, and higher yield. Organized by specific plant challenges, this book presents expert insights from around the globe, providing updated knowledge of CRISPR with an emphasis on facing climate change and supporting sustainable agriculture. This volume in the Genome Modified Plants and Microbes in Food and Agriculture series will be valuable for researchers, academics, and advanced-level students seeking to understand and advance the use of CRISPR technologies toward the UN Sustainable Development Goals and the Paris Climate Agreement.

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  • What is CRISPR exactly?

    CRISPR, which stands for Clustered Regularly Interspaced Short Palindromic Repeats, is a revolutionary gene-editing technology that allows scientists to make precise changes to an organism's DNA. It is derived from a natural defense mechanism found in bacteria, which uses RNA molecules and Cas proteins to target and cut specific DNA sequences. This technology has the potential to revolutionize fields such as medicine, agriculture, and biotechnology by enabling the modification of genes to treat genetic disorders, create disease-resistant crops, and develop new therapies.

  • What is the order of CRISPR-Cas?

    The order of CRISPR-Cas refers to the sequence of events that occur during the CRISPR-Cas immune response in bacteria and archaea. The order begins with the acquisition of foreign DNA sequences, which are then integrated into the CRISPR array. Next, the CRISPR array is transcribed and processed into CRISPR RNA (crRNA). The crRNA then guides the Cas proteins to the matching foreign DNA or RNA sequences, leading to their degradation. This sequence of events allows the CRISPR-Cas system to recognize and defend against specific invading genetic material.

  • What are alternatives to the CRISPR-Cas method?

    Alternative methods to CRISPR-Cas for genome editing include zinc finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs). These methods also use engineered proteins to target specific DNA sequences for modification. Another alternative is base editing, which allows for precise changes to individual DNA bases without cutting the DNA double helix. Additionally, RNA interference (RNAi) can be used to selectively silence gene expression without directly modifying the DNA sequence. Each of these methods has its own advantages and limitations, making them suitable for different applications in genetic research and biotechnology.

  • What is the correct implementation of CRISPR-Cas?

    The correct implementation of CRISPR-Cas involves using a guide RNA to target a specific DNA sequence, and the Cas protein to make a cut at that location. This allows for precise editing of the DNA sequence, either by introducing a desired mutation or by inserting a new sequence. It is important to carefully design the guide RNA to ensure specificity and efficiency of the editing process. Additionally, proper controls and validation experiments should be performed to confirm the accuracy of the editing.

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  • A History of the Human Brain : From the Sea Sponge to CRISPR, How Our Brain Evolved
    A History of the Human Brain : From the Sea Sponge to CRISPR, How Our Brain Evolved

    “Crack open this book and take a read. You will be transported, illuminated, and delighted.” —Psychology Today Just 125,000 years ago, humanity was on a path to extinction, until a dramatic shift occurred.We used our mental abilities to navigate new terrain and changing climates.We hunted, foraged, tracked tides, shucked oysters—anything we could do to survive.Before long, our species had pulled itself back from the brink and was on more stable ground.What saved us? The human brain—and its evolutionary journey is unlike any other.In A History of the Human Brain, Bret Stetka takes us on this far-reaching journey, explaining exactly how our most mysterious organ developed.From the brain’s improbable, watery beginnings to the marvel that sits in the head of Homo sapiens today, Stetka covers an astonishing progression, even tackling future brainy frontiers such as epigenetics and CRISPR.Clearly and expertly told, this intriguing account is the story of who we are.By examining the history of the brain, we can begin to piece together what it truly means to be human.

    Price: 20.00 £ | Shipping*: 3.99 £
  • Altered Inheritance : CRISPR and the Ethics of Human Genome Editing
    Altered Inheritance : CRISPR and the Ethics of Human Genome Editing

    A leading bioethicist offers critical insights into the scientific, ethical, and political implications of human genome editing. Designer babies, once found only in science fiction, have become a reality.We are entering a new era of human evolution with the advent of a technology called CRISPR, which allows scientists to modify our genes.Although CRISPR shows great promise for therapeutic use, it raises thorny ethical, legal, political, and societal concerns because it can be used to make permanent changes to future generations.What if changes intended for the good turn out to have unforeseen negative effects?What if the divide between the haves and have-nots widens as a result?Who decides whether we genetically modify human beings and, if so, how?Françoise Baylis insists that we must all have a role in determining our future as a species.The scientists who develop and use genome-editing tools should not be the only ones making decisions about future uses of the technology.Such decisions must be the fruit of a broad societal consensus.Baylis argues that it is in our collective interest to assess and steer the development and implementation of biomedical technologies.Members of the public with different interests and diverse perspectives must be among the decision makers; only in this way can we ensure that societal concerns are taken into account and that responsible decisions are made.We must be engaged and informed, think critically, and raise our voices as we create our future together. Sharp, rousing, timely, and thought-provoking, Altered Inheritance is essential reading.The future of humanity is in our hands.

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  • Introduction to CRISPR-Cas9 Techniques : Strategies for the Laboratory and the Classroom
    Introduction to CRISPR-Cas9 Techniques : Strategies for the Laboratory and the Classroom

    This open-access textbook provides an in-depth introduction into the CRISPR-cas9 technology and explores its use across the gamut of biological model systems. As the subject has risen from a significant new discovery to a mainstream molecular biology practice, it is essential that students of molecular biology understand the fundamentals behind CRISPR-Cas9 technology and how it may be employed efficiently and ethically in research.This volume, edited by experts in both, molecular biology and undergraduate education, will teach not only the fundamentals of using CRISPR-Cas9, but also how to successfully employ this technology in classroom settings. The book is written for undergraduates and advanced high school classes in the area of molecular biology, genetics, genomics and biological engineering and will provide a perfect tool for undergraduate lecturers to prepare their classes. 

    Price: 69.99 £ | Shipping*: 0.00 £
  • CRISPR-Cas-Based Genome Editing for Treating Human Diseases - Part B : Volume 210
    CRISPR-Cas-Based Genome Editing for Treating Human Diseases - Part B : Volume 210

    CRISPR-Cas-Based Genome Editing for Treating Human Diseases, Part B represents CRISPR-Cas systems for genome editing.Currently, CRISPR-Cas systems have been proven to be a key technology for targeted genome editing, which is acting as a simple, rapid, and cost-effective solution.Chapters in this release include Current approaches in CRISPR –Cas systems for metabolic disorders, Recent progress in CRISPR –Cas systems for CRISPR for retinal diseases, Recent progress in CRISPR –Cas systems for cataract and blindness, Advances in CRISPR –Cas systems for muscular dystrophy, Recent development in CRISPR –Cas systems for cardiac disease, Current approaches in CRISPR –Cas systems for diabetes, and much more. Additional sections cover Advances in CRISPR –Cas systems for liver disease, Advances in CRISPR –Cas systems for lung disease, Advances in CRISPR –Cas systems for kidney diseases, Current progress in CRISPR –Cas systems for rare disease, Advances in CRISPR –Cas systems for heredity disease, Recent progress in CRISPR –Cas systems for neurological disorders, and CRISPR challenges in clinical developments.

    Price: 119.00 £ | Shipping*: 0.00 £
  • Why don't dictatorships use CRISPR to gain world domination?

    Dictatorships may not use CRISPR for world domination for several reasons. Firstly, the technology is still relatively new and its long-term effects are not fully understood, so there may be concerns about the potential risks and unintended consequences of using CRISPR for such purposes. Additionally, the international community closely monitors developments in genetic engineering, and the use of CRISPR for nefarious purposes could lead to severe diplomatic and economic repercussions. Furthermore, the ethical and moral implications of using CRISPR for world domination would likely be a significant deterrent for many individuals and organizations.

  • Can you please explain Crispr in your own words?

    Sure! CRISPR is a revolutionary technology that allows scientists to make precise changes to an organism's DNA. It works by using a special protein called Cas9 to target and cut specific sequences of DNA, allowing researchers to add, remove, or modify genes with great accuracy. This has huge potential for applications in medicine, agriculture, and biotechnology, as it could lead to new treatments for genetic diseases, improved crop yields, and advancements in genetic engineering.

  • Who is an expert on CRISPR for a research paper?

    An expert on CRISPR for a research paper would typically be a scientist or researcher who has extensive experience and knowledge in the field of CRISPR technology. This individual would have a background in molecular biology, genetics, or a related field, and would have published research articles or studies related to CRISPR. They would be able to provide in-depth insights, analysis, and interpretations of the latest advancements, applications, and ethical considerations surrounding CRISPR technology. Collaborating with such an expert would ensure the research paper is well-informed, credible, and up-to-date with the current state of CRISPR research.

  • When will the viral genome be cut with CRISPR-Cas?

    The viral genome will be cut with CRISPR-Cas when the Cas protein, guided by the CRISPR RNA, recognizes the specific target sequence on the viral genome. Once the Cas protein binds to the target sequence, it will create a double-strand break in the viral DNA, effectively cutting the genome. This process can occur at any time after the CRISPR-Cas system has been activated and the Cas protein has located the target sequence on the viral genome.

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